FenuMat: A Natural Delivery Format for Phyto and Micro-Nutrients

The burgeoning interest in the health benefits of phytonutrients derived from spices and herbs has significantly increased the demand for thoroughly researched, phytonutrient-rich  extracts. These natural agents are sought for their health-promoting and health-protecting properties. Despite the demonstrated efficacy of numerous phytonutrients and micronutrients in various pharmacological studies, their poor oral bioavailability often hampers their effectiveness against diseases such as cardiovascular, neurodegenerative, metabolic disorders, obesity, and cancer.

Consequently, there is a pressing need for safe and cost-effective delivery systems that can ensure significant quantities of these nutrients reach the bloodstream upon oral consumption. Most current methods rely on synthetic emulsifiers or polymer-based nanoparticles used in pharmaceuticals, but FenuMat offers a revolutionary alternative.

FenuMat is a 100% natural, food-grade micronutrient delivery technology, protected by patents, based on soluble dietary fiber (galactomannans) extracted from fenugreek seeds. The distinctive chemical structure of fenugreek galactomannans provides an ideal platform for loading both oils and hydrophobic molecules under optimized conditions. This water- based process, free from organic solvents and synthetic excipients, positions FenuMat as the first commercially viable, green approach in phytonutrient delivery.

Specialties of FenuMat

• Natural and Food-Grade: Derived from the spice fenugreek, FenuMat utilizes a specialized galactomannan
• Organic Potential: FenuMat can be produced as an organic product.
• Versatile Form: Available as a powder suitable for soft gels, tablets, sachets, and capsules, enhancing storage and shelf life.
• Enhanced Stability: The gel matrix of lipids within galactomannan is highly permeable, ensuring long shelf life and resistance to rancidity.
• Clean Label: FenuMat meets clean label standards—vegan, halal, kosher, allergen-free, and non-GMO.
• High Bioactive Loading: Capable of high bioactive molecule encapsulation.

Hybrid-FenuMat Technology

The hybrid-FenuMat technology integrates fenugreek galactomannan as a biopolymer matrix for the uniform impregnation of bioactive molecules (lipidated CAAS). This innovation protects liposomal forms from common issues such as poor in vivo stability and rapid elimination.

Compared to synthetic polymers, hybrid-FenuMat technology offers significant advantages for biomedical applications by minimizing burst release, improving water solubility, and enhancing the bioavailability of encapsulated bioactive molecules.

• Improved Stability and Administration: Enhances both drug formulation stability and administration routes.
• Overcoming Liposomal Drawbacks: Addresses issues like chemical changes in liposomes and enhances stability under stomach and storage conditions.
• Reduced Chemical Stabilizers: Minimizes the need for chemical stabilizers and improves drug loading efficiency.
• Enhanced Oral Bioavailability: Reduces opsonization, thereby improving oral bioavailability.
• Environmental Protection: The fenugreek galactomannan hydrogel network provides a “capping effect,” stabilizing liposomes against harsh environmental conditions.

Successful Formulations

• FenuMat Vitamin C
• FenuMat Resveratrol
• FenuMat Quercetin

FenuMat represents a paradigm shift in the delivery of phyto and micronutrients, emphasizing naturality, adaptability, and the ability to address the limitations faced by current industry practices.